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Antikörper

BAD antibody - C-terminal region

Produktgrößen
25ul
£177,00
ARP30325-P050-25UL
100 ul
£412,00
ARP30325-P050-100UL
Über dieses Produkt
SKU:
ARP30325-P050
Zusätzliche Namen:
BBC2; BCL2L8
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
BAD is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2; and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase; as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2; and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase; as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Gendetails:
BCL2-associated agonist of cell death
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human BAD
Molekulargewicht:
18kDa
Proteindetails:
Bcl2 antagonist of cell death
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody