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Antikörper

CALR Antibody - C-terminal region

Produktgrößen
25ul
£177,00
ARP30114-P050-25UL
100 ul
£412,00
ARP30114-P050-100UL
Über dieses Produkt
SKU:
ARP30114-P050
Zusätzliche Namen:
RO; CRT; SSA; cC1qR; HEL-S-99n
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus; suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR; which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies; it is highly conserved among species; and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium.
Gendetails:
Calreticulin
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human CALR
Molekulargewicht:
48kDa
Proteindetails:
Calreticulin
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody