CDH1 Blocking peptide
Produktgrößen
100ug
£183,00
AAP97001-100UG
Über dieses Produkt
- SKU:
- AAP97001
- Zusätzliche Namen:
- UVO; CDHE; ECAD; LCAM; Arc-1; BCDS1; CD324
- Weitere Details:
- This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants; at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats; a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric; breast; colorectal; thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation; invasion; and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16.
- Gendetails:
- UVO; CDHE; ECAD; LCAM; Arc-1; CD324
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage; store at -20C. Avoid repeat freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides