BCL10 Blocking peptide
Produktgrößen
100ug
£183,00
AAP88067-100UG
Über dieses Produkt
- SKU:
- AAP88067
- Zusätzliche Namen:
- CLAP; mE10; CIPER; IMD37; c-E10; CARMEN
- Weitere Details:
- This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD); and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9; 10; 11 and 14; which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1; a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB; and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants.
- Gendetails:
- B-cell CLL/lymphoma 10
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage; store at -20C. Avoid repeat freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides