BAG4 Blocking peptide
Produktgrößen
100ug
£183,00
AAP81938-100UG
Über dieses Produkt
- SKU:
- AAP81938
- Zusätzliche Namen:
- SODD; BAG-4
- Weitere Details:
- The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2; Raf-protein kinase; steroid hormone receptors; growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus; which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3); and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
- Gendetails:
- BCL2 associated athanogene 4
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage; store at -20C. Avoid repeat freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides