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SMARCE1

Produktgrößen
100ug
£183,00
AAP38224-100UG
Über dieses Produkt
SKU:
AAP38224
Zusätzliche Namen:
CSS5; BAF57
Weitere Details:
SMARCE1 is part of the large ATP-dependent chromatin remodeling complex SWI/SNF; which is required for transcriptional activation of genes normally repressed by chromatin. The protein; either alone or when in the SWI/SNF complex; can bind to 4-way junction DNA; which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain; but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins; this protein has no yeast counterpart.The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF; which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein; either alone or when in the SWI/SNF complex; can bind to 4-way junction DNA; which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain; but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins; this protein has no yeast counterpart.
Gendetails:
SWI/SNF related; matrix associated; actin dependent regulator of chromatin; subfamily e; member 1
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage; store at -20C. Avoid repeat freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Buffers & General Consumables: Others