Polatuzumab vedotin-piiq (ADC)
Produktgrößen
1 mg
£1180,00
DHE26399-1MG
5 mg
£4366,00
DHE26399-5MG
Über dieses Produkt
- SKU:
- DHE26399
- Zusätzliche Namen:
- Polivy
- translate.label.attr.clone:
- Polatuzumab vedotin-piiq
- Klonalität:
- Monoclonal, Recombinant Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Polatuzumab vedotin (Polivy) is an ADC consisting of a CD79b-directed antibody and Monomethyl auristatin E (MMAE) that can be used in combination with bendamustine and rituximab for the treatment of adult patients with at least two relapses or refractory diffuse large B-cell lymphoma. Polatuzumab vedotin binds to CD79b and is internalized by tumor cells. MMAE is cleaved from cells by lysosomal protease and promotes tumor cell apoptosis by inhibiting microtubule formation.
- Immunogen:
- CD79b
- Physischer Zustand:
- Liquid
- Reinheit:
- >90% as determined by sec.
- Aufreinigung:
- Ion Exchange
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles., -70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- AntibodySystem
- Typ:
- Antibody: Recombinant Antibodies