Fluorescent Human SSTR2 Full Length Protein (VLP)
Produktgrößen
20 ug
£1237,00
SS2-HF2G3-20UG
100 ug
£1867,00
SS2-HF2G3-100UG
500 ug
£5046,00
SS2-HF2G3-500UG
Über dieses Produkt
- SKU:
- SS2-HF2G3
- Buffer:
- PBS, Arginine, pH7.4
- Weitere Details:
- Somatostatin is a peptide with a potent and broad antisecretory action, which makes it an invaluable drug target for the pharmacological management of pituitary adenomas and neuroendocrine tumors. Somatostatin receptors (SSTR1, 2A and B, 3, 4 and 5) belong to the G protein coupled receptor family and have a wide expression pattern in both normal tissues and solid tumors. Investigating the function of each SSTR in several tumor types has provided a wealth of information about the common but also distinct signaling cascades that suppress tumor cell proliferation, survival and angiogenesis. This provided the rationale for developing multireceptor-targeted somatostatin analogs and combination therapies with signaling-targeted agents such as inhibitors of the mammalian (or mechanistic) target of rapamycin (mTOR). The ability of SSTR to internalize and the development of rabiolabeled somatostatin analogs have improved the diagnosis and treatment of neuroendocrine tumors.
- Immunogen:
- SSTR2
- Molekulargewicht:
- 45.3 kDa | 83.1 kDa
- Physischer Zustand:
- Liquid
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- -70[o]C Avoid freeze/thaw cycles. Protect from light.
- Hersteller:
- ACRO Biosystems
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
