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Proteine und Peptide

Human SSTR2 Full Length Protein (VLP)

Produktgrößen
20 ug
£1237,00
SS2-H5216-20UG
100 ug
£1867,00
SS2-H5216-100UG
500 ug
£5046,00
SS2-H5216-500UG
Über dieses Produkt
SKU:
SS2-H5216
Zusätzliche Namen:
Smstr2|Somatostatin R2|somatostatin receptor 2|somatostatin receptor type 2|SomatostatinR2|SRIF-1|SS-2-R|SS2-R|SS2R|SST2|SSTR2
Buffer:
PBS
Weitere Details:
Somatostatin is a peptide with a potent and broad antisecretory action, which makes it an invaluable drug target for the pharmacological management of pituitary adenomas and neuroendocrine tumors. Somatostatin receptors (SSTR1, 2A and B, 3, 4 and 5) belong to the G protein coupled receptor family and have a wide expression pattern in both normal tissues and solid tumors. Investigating the function of each SSTR in several tumor types has provided a wealth of information about the common but also distinct signaling cascades that suppress tumor cell proliferation, survival and angiogenesis. This provided the rationale for developing multireceptor-targeted somatostatin analogs and combination therapies with signaling-targeted agents such as inhibitors of the mammalian (or mechanistic) target of rapamycin (mTOR). The ability of SSTR to internalize and the development of rabiolabeled somatostatin analogs have improved the diagnosis and treatment of neuroendocrine tumors.
Immunogen:
SSTR2
Molekulargewicht:
45.3 kDa | 56.1 kDa
Physischer Zustand:
Liquid
Versandbedingungen:
Dry Ice
Lagerbedingungen:
-70[o]C
Hersteller:
ACRO Biosystems
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins