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Proteine und Peptide

Human TNFSF11 / RANKL / CD254 Protein, premium grade

Produktgrößen
20 ug
£195,00
RAL-H5217-20UG
50 ug
£366,00
RAL-H5217-50UG
1 mg
£2344,00
RAL-H5217-1MG
Über dieses Produkt
SKU:
RAL-H5217
Zusätzliche Namen:
CD254|ODF|OPGL|RANKL|TRANCE
Buffer:
PBS
Weitere Details:
Receptor activator of nuclear factor kappa-B ligand (RANKL), also known as tumor necrosis factor ligand superfamily member 11 (TNFSF11), TNF-related activation-induced cytokine (TRANCE), osteoprotegerin ligand (OPGL), and osteoclast differentiation factor (ODF), is known as a type II membrane protein and is a member of the tumor necrosis factor (TNF) superfamily. RANKL, through its ability to stimulate osteoclast formation and activity, is a critical mediator of bone resorption and overall bone density. Some findings also suggestion some cancer cells, particularly prostate cancer cells, can activate an increase in bone remodeling and ultimately increase overall bone production.[17] This increase in bone remodeling and bone production increases the overall growth of bone metastasizes. The overall control of bone remodeling is regulated by the binding of RANKL with its receptor or its decoy receptor, respectively, RANK and OPG.
Immunogen:
TNFSF11
Molekulargewicht:
20.5 kDa
Physischer Zustand:
Powder
Versandbedingungen:
Ambient
Lagerbedingungen:
-20[o]C
Hersteller:
ACRO Biosystems
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human TNFSF11 Protein, premium grade on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human TNFSF11 Protein, premium grade (Cat. No. RAL-H5217) at 2 ug/mL (100 uL/well) can bind Human RANK, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. RAK-H5251) with a linear range of 0.1-4 ng/mL (QC tested).
Immobilized Human TNFSF11 Protein, premium grade (Cat. No. RAL-H5217) at 2 ug/mL (100 uL/well) can bind Human Osteoprotegerin, His Tag (Cat. No. TNB-H5220) with a linear range of 0.01-0.313 ug/mL (Routinely tested).