Monoclonal Anti-PNU-159682 Antibody, Rabbit IgG (M1E11)
Produktgrößen
100 ug
£324,00
PNU-MY2372-100UG
1 mg
£1955,00
PNU-MY2372-1MG
Über dieses Produkt
- SKU:
- PNU-MY2372
- Buffer:
- PBS (pH 7.4)
- translate.label.attr.clone:
- M1E11
- Klonalität:
- Monoclonal
- Weitere Details:
- PNU-159682 is a topoisomerase II inhibitor serving as a payload for antibody-drug conjugates (ADCs). Its mechanism of action involves stabilizing the complex formed by topoisomerase II and DNA, blocking DNA repair and replication processes, and thereby inducing cancer cell apoptosis. Some ADCs containing PNU-159682 have entered the preclinical research stage, showing targeted killing activity in solid tumor models, with particularly significant effects on tumors with high topoisomerase II expression.
- Immunogen:
- PNU-159682
- Physischer Zustand:
- Powder
- Reaktivitäten:
- Rabbit
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ACRO Biosystems
- Typ:
- Antibody: Monoclonal Antibody
