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Proteine und Peptide

Human IL-5 Protein, premium grade

Produktgrößen
50 ug
£460,00
IL5-H5214-50UG
500 ug
£2014,00
IL5-H5214-500UG
1 mg
£3068,00
IL5-H5214-1MG
Über dieses Produkt
SKU:
IL5-H5214
Buffer:
PBS
Weitere Details:
Interleukin 5 (IL5) is an interleukin produced by type-2 T helper cells and mast cells. IL-5 is a 115-amino acid (in human, 133 in the mouse) -long TH2 cytokine that is part of the hematopoietic family. Unlike other members of this cytokine family (namely interleukin 3 and GM-CSF), this glycoprotein in its active form is a homodimer. Interleukin-5 has long been associated with the cause of several allergic diseases including allergic rhinitis and asthma, wherein a large increase in the number of circulating, airway tissue, and induced sputum eosinophils have been observed. Given the high concordance of eosinophils and, in particular, allergic asthma pathology, it has been widely speculated that eosinophils have an important role in the pathology of this disease. Drugs that target IL-5 are mepolizumab and reslizumab.
Immunogen:
IL-5
Molekulargewicht:
13.1 kda
Physischer Zustand:
Powder
Versandbedingungen:
Ambient
Lagerbedingungen:
-20[o]C
Hersteller:
ACRO Biosystems
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human IL-5 Protein, premium grade on SDS-PAGE under reducing (R) and under non-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human IL-5 Protein, premium grade (Cat. No. IL5-H5214) at 5 ug/mL (100 uL/well) can bind Biotinylated Human IL-5 R alpha Protein, Avitag,Fc Tag (Cat. No. ILA-H82F5) with a linear range of 0.6-10 ng/mL (QC tested).