Human IL-31 Protein, premium grade
Produktgrößen
20 ug
£195,00
IL1-H5219-20UG
50 ug
£389,00
IL1-H5219-50UG
1 mg
£2768,00
IL1-H5219-1MG
Über dieses Produkt
- SKU:
- IL1-H5219
- Buffer:
- PBS
- Weitere Details:
- IL-31 is an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens. Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. It has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. May function in skin immunity. IL-31 is produced by a variety of cells, namely type 2 helper (TH2) T-cells. IL-31 sends signals through a receptor complex made of IL-31RA and oncostatin M receptor B Beta (OSMRB Beta) expressed in immune and epithelial cells. These signals activate three pathways: ERK1/2 MAP kinase, PI3K/AKT, and JAK1/2 signaling pathways.
- Immunogen:
- IL-31
- Molekulargewicht:
- 15.8 kDa
- Physischer Zustand:
- Powder
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ACRO Biosystems
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
