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Proteine und Peptide

Human IFN-alpha/beta R2 Protein, (MALS & BLI verified)

Produktgrößen
100 ug
£313,00
IF2-H5224-100UG
1 mg
£2155,00
IF2-H5224-1MG
Über dieses Produkt
SKU:
IF2-H5224
Zusätzliche Namen:
beta receptor 2|IFN-alpha|IFN-R-2|IFNABR|IFNAR2|IFNARB
Buffer:
PBS
Weitere Details:
Interferon alpha/beta receptor 2 (IFNAR2) is also known as IFN-alpha binding protein, IFN-alpha/beta receptor 2, Type I interferon receptor 2, IFNABR and IFNARB, which is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. IFNAR2 can associate with IFNAR1 to form the type I interferon receptor. IFNAR2 is a receptor for interferons alpha and beta.IFNAR2 involves in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 of IFNAR2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 of IFNAR2 is a potent inhibitor of type I IFN receptor activity.Genetic variations in IFNAR2 influence susceptibility to hepatitis B virus (HBV) infection.
Immunogen:
IFN-alpha/beta R2
Molekulargewicht:
25.8 kDa
Physischer Zustand:
Powder
Versandbedingungen:
Ambient
Lagerbedingungen:
-20[o]C
Hersteller:
ACRO Biosystems
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human IFNAR2, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human IFNAR2, His Tag (Cat. No. IF2-H5224) at 5 ug/mL (100 uL/well) can bind Human IFN-alpha 2a (R46K) Protein, Fc Tag (Cat. No. IFA-H5253) with a linear range of 1-40 ng/mL (Routinely tested).
Immobilized Human IFNAR2, His Tag (Cat. No. IF2-H5224) at 5 ug/mL (100 uL/well) can bind Human IFN-beta Protein, Fc Tag (Cat. No. IFB-H5254) with a linear range of 0.03-2 ng/mL (Routinely tested).