PE-Labeled Monoclonal Anti-Human CD31 Antibody, Mouse IgG1 (AS580) (0.03% Proclin)
Produktgrößen
50 tests
£207,00
FABM033-01-50TESTS
200 tests
£742,00
FABM033-01-200TESTS
Über dieses Produkt
- SKU:
- FABM033-01
- Anwendung:
- Flow Cytometry
- Buffer:
- PBS (pH 7.4) containing 0.03% ProClin 300 and 0.2% BSA
- translate.label.attr.clone:
- AS580
- Klonalität:
- Monoclonal
- Konjugat:
- R-PE
- Weitere Details:
- Cluster of Differentiation 31 (CD31) is also known as Platelet endothelial cell adhesion molecule (PECAM-1), is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, macrophages and Kupffer cells, granulocytes, T / NK cells, lymphocytes, megakaryocytes, osteoclasts, neutrophils, certain tumors, and is the only known member of the CAM family on platelets. CD31 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. CD31 plays a key role in removing aged neutrophils from the body. CD31 mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin A AlphavB Beta3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development. In addition, it has been shown that CD31 expression is up-regulated by LPS stimulation, and might function as a feedback negative regulator of LPS inflammatory response in macrophages.
- Immunogen:
- CD31
- Physischer Zustand:
- Liquid
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Protect from light.
- Hersteller:
- ACRO Biosystems
- Typ:
- Antibody: Monoclonal Antibody
