Monoclonal Anti-Duocarmycin Antibody, Rabbit IgG (M1E06)
Produktgrößen
100 ug
£324,00
DUN-MY2287-100UG
1 mg
£1955,00
DUN-MY2287-1MG
Über dieses Produkt
- SKU:
- DUN-MY2287
- Buffer:
- PBS (pH 7.4)
- translate.label.attr.clone:
- M1E06
- Klonalität:
- Monoclonal
- Weitere Details:
- Duocarmycin, a DNA minor groove-binding alkylating agent, acts as a payload in antibody-drug conjugates (ADCs) by selectively targeting AT-rich regions of DNA. It forms covalent bonds with the N3 position of adenine, inducing strand breaks and apoptosis through S-phase cell cycle arrest . This mechanism bypasses multidrug resistance pathways, making it potent against aggressive tumors.
- Immunogen:
- Duocarmycin
- Physischer Zustand:
- Powder
- Reaktivitäten:
- Rabbit
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ACRO Biosystems
- Typ:
- Antibody: Monoclonal Antibody
