Human Claudin-9 / CLDN9 Full Length Protein (VLP)
Produktgrößen
20 ug
£1237,00
CL9-H52P5-20UG
100 ug
£1867,00
CL9-H52P5-100UG
500 ug
£5046,00
CL9-H52P5-500UG
Über dieses Produkt
- SKU:
- CL9-H52P5
- Buffer:
- PBS, Arginine, pH7.4
- Weitere Details:
- Claudin-9 belongs to the claudin family. Claudins constitute integral membrane proteins responsible for solute and electrolyte permeability of the tight junction that serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Tight junctions also play a critical role in maintaining cell polarity and signal transductions. Claudin-9 creates charge specific channels in the paracellular space, plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity, is required to preserve sensory cells in the hearing organ because claudin-9-defective tight junctions fail to shield the basolateral side of hair cells from the K+-rich endolymph. Its ion barrier function is essential in the cochlea, but appears to be dispensable in other organs. Is one of the entry cofactors for hepatitis C virus; it enables HCV entry into target cells just as efficiently as CLDN1.
- Immunogen:
- Claudin-9
- Molekulargewicht:
- 24.7 kDa | 83.1 kDa
- Physischer Zustand:
- Liquid
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- -70[o]C
- Hersteller:
- ACRO Biosystems
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
