Fluorescent Human Claudin-18.2 Full Length Protein (VLP)
Produktgrößen
20 ug
£1237,00
CL2-HF218-20UG
100 ug
£1867,00
CL2-HF218-100UG
500 ug
£5046,00
CL2-HF218-500UG
Über dieses Produkt
- SKU:
- CL2-HF218
- Zusätzliche Namen:
- Claudin-18|Claudin-18.2|CLDN18
- Buffer:
- PBS
- Weitere Details:
- Claudins (CLDNs) are a family of proteins that form tight junctions and maintain the polarity of epithelial and endothelial cells. CLDN18 is specifically expressed in the stomach and lung. Of the two CLDN18 isoform transcripts produced by alternative splicing, CLDN18.2 is a highly selective gastric lineage marker that determines the gastric phenotype in a neoplastic condition, whereas CLDN18.1 is lung specific. CLDN18.2 is a highly selective gastric lineage antigen expressed exclusively on short-lived differentiated gastric epithelial cells where it has only limited accessibility to antibody drugs.14,15 CLDN18.2 is maintained during the course of malignant transformation and thus frequently displayed on the surface of human gastric cancer cells.
- Immunogen:
- Claudin-18.2
- Molekulargewicht:
- 27.7 kDa | 83.1 kDa
- Physischer Zustand:
- Liquid
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- -70[o]C Avoid freeze/thaw cycles. Protect from light.
- Hersteller:
- ACRO Biosystems
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
