Rhesus macaque CCR8 Full Length Protein (VLP)
Produktgrößen
20 ug
£1237,00
CC8-R52P3-20UG
100 ug
£1872,00
CC8-R52P3-100UG
500 ug
£5040,00
CC8-R52P3-500UG
Über dieses Produkt
- SKU:
- CC8-R52P3
- Buffer:
- PBS, Arginine, pH7.4
- Weitere Details:
- CCR8 is a key chemokine receptor primarily expressed on regulatory T cells (Tregs) infiltrating the tumor microenvironment. It plays a decisive role in mediating immunosuppression by facilitating Treg recruitment and activation. Emerging research highlights the interaction between CCR8 and glycosaminoglycans (GAGs), which serve as essential co-receptors. GAGs facilitate the presentation of ligands like CCL1 to CCR8, effectively concentrating chemokines on the cell surface to enhance signaling efficiency. Targeting the CCR8-GAG axis represents a sophisticated strategy for selective Treg depletion, offering high precision for cancer immunotherapy while minimizing systemic autoimmune side effects.
- Immunogen:
- CCR8
- Physischer Zustand:
- Liquid
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- -70[o]C
- Hersteller:
- ACRO Biosystems
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
