GENPower[TM] LbCas12a Nuclease (2.5 ug/uL), low endotoxin (MALS verified)
Produktgrößen
50 ug
£707,00
CAA-L5149-50UG
100 ug
£789,00
CAA-L5149-100UG
500 ug
£1054,00
CAA-L5149-500UG
Über dieses Produkt
- SKU:
- CAA-L5149
- Zusätzliche Namen:
- cas12a|Cpf1|CRISPR-associated endonuclease Cas12a|CRISPR-associated endonuclease Cpf1
- Buffer:
- 20 mM NaAC, 500 mM NaCl, pH6.0
- Weitere Details:
- Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated endonuclease from Lachnospiraceae bacterium, Cas12a, also known as Cpf1, is a 1200-1500 amino-acids long monomeric protein that belongs to the CRISPR/Cas system , an adaptive immune system of prokaryotes that has now become a powerful tool for genome editing. CRISPR/Cas12a belongs the class II (type 5) of the CRISPR/Cas system that is defined by a single-subunit effector. Cas12a has recently emerged as an alternative for Cas9, due to its distinct features such as the ability to target T-rich motifs, no need for trans-activating crRNA, inducing a staggered double-strand break and potential for both RNA processing and DNA nuclease activity. In addition, Cas12a is able to process more structured pre-CRISPR/RNA(crRNA) molecules into mature crRNAs which allows the possibility to use both mature or pre-crRNA for genome editing purposes. All these features make the CRISPR/Cas12a system a valuable genome-engineering tool. CRISPR-Cas12a has been successfully used to edit genomes in many mammalians cells and plants.
- Immunogen:
- Cas12a
- Molekulargewicht:
- 147.6 kDa
- Physischer Zustand:
- Liquid
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ACRO Biosystems
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes