Human C5AR1 Full Length Protein (VLP)
Produktgrößen
20 ug
£936,00
C51-H52P4-20UG
100 ug
£1572,00
C51-H52P4-100UG
500 ug
£4739,00
C51-H52P4-500UG
Über dieses Produkt
- SKU:
- C51-H52P4
- Buffer:
- PBS, Arginine, pH7.4
- Weitere Details:
- Complement Component 5a Receptor 1 (C5aR1), also known as CD88, is a high-affinity G protein-coupled receptor (GPCR) essential for mediating potent inflammatory responses. In the tumor microenvironment, C5aR1 activation on myeloid-derived suppressor cells (MDSCs) facilitates immune evasion and metastasis. Crucially, C5aR1 interacts with glycosaminoglycans (GAGs), such as heparin, which act as co-receptors or modulators. These C5aR1-GAG interactions influence ligand recruitment and receptor signaling, making this axis a prime target for developing therapeutic antibodies and small-molecule inhibitors in oncology and autoimmune disorders.
- Immunogen:
- C5AR1
- Physischer Zustand:
- Liquid
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- -70[o]C
- Hersteller:
- ACRO Biosystems
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
