SARS-CoV-2 (Spike RBD) IgG Serological ELISA Kit with false positive control
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1 X 96 Tests
£859,00
90-7004-96T
Über dieses Produkt
- SKU:
- 90-7004
- Weitere Details:
- Coronaviruses (CoVs) are enveloped non-segmented positive-sense RNA virus for human and vertebrates. They are classified into four types; α-CoV; α-CoV; α-CoV; and α-CoV. They can infect respiratory; gastrointestinal; hepatic; and central nervous system of human and many other wild animals. The family Coronaviridae constantly circulate in the human population and mainly cause mild respiratory diseases. In December 2019; a new severe acute respiratory syndrome ï¢-coronavirus called SARS-CoV-2 (or 2019-nCoV) has emerged; which causes an epidemic of acute respiratory syndrome (called coronavirus human disease 2019 or COVID-19).Typical clinical symptoms of these patients are dry cough; fever; breathing difficulties; headache and pneumonia. Disease onset may result in progressive respiratory failure and even death. SARS-CoV-2 has similarity to SARS-CoV. SARS-CoV-2 virus contains 4 structural proteins; spike (S); envelope (E); membrane (M) and nucleocapsid. The spike protein (S) is a transmembrane protein; composed of the S1 subunit and S2 subunit. The S1 subunit contains a receptor binding domain (RBD); which binds to the cell surface receptor Angiotensin-Converting Enzyme 2 (ACE2) present at the surface of epithelial cells; causing infection of human respiratory cells.During an infection; IgM antibody appears first; followed by IgA on mucosal surfaces or IgG in the serum. The spike (S); mainly the RBD domain and the nucleocapsid (N) are the main immunogens of Coronavirus leading to antibody answer.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Please refer to the Manual
- Hersteller:
- Abeomics
- Typ:
- Assay Kits:ELISAs
- Datenblatt des Herstellers:download_pdf.php