Anti-MDR3 Monoclonal Antibody (Clone:IHC621)
Produktgrößen
0.1 ml
£664,00
44-1165-0.1ML
1 ml
£1681,00
44-1165-1ML
Über dieses Produkt
- SKU:
- 44-1165
- Zusätzliche Namen:
- Phosphatidylcholine translocator ABCB4; ATP-binding cassette sub-family B member 4; Multidrug resistance protein 3; P-glycoprotein 3
- translate.label.attr.clone:
- IHC621
- Klonalität:
- Monoclonal
- Weitere Details:
- Multidrug Resistance 3 (MDR3); also known as ATP Binding Cassette Subfamily B Member 4 (ABCB4); is a membrane-associated protein belonging to the superfamily of ATP-binding cassette transporters. MDR3 is an energy-dependent phospholipid efflux translocator that mediates the translocation of phosphatidylcholine across the canalicular membrane of the hepatocyte; and also acts as a positive regulator of biliary lipid secretion. Defects in MDR3 are associated with progressive familial intrahepatic cholestasis type 3 and gallbladder disease type 1. Co-overexpression of MDR3 and MRP1 has been documented as correlating with blastemal subtype and high-risk prognosis of Wilms' tumor patients.
- Format:
- Purified
- Host:
- Mouse
- Aufreinigung:
- Protein A/G Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2[o]C - 8[o]C.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg