Anti-PD-L1 Rabbit Monoclonal Antibody (Clone:IHC411)
Produktgrößen
0.1 ml
£583,00
44-1069-0.1ML
0.5 ml
£918,00
44-1069-0.5ML
Über dieses Produkt
- SKU:
- 44-1069
- translate.label.attr.clone:
- IHC411
- Klonalität:
- Monoclonal
- Weitere Details:
- Programmed Death-Ligand 1 (PD-L1); also known as CD274 or B7 Homolog 1 (B7-H1); is a transmembrane protein involved in suppressing the immune system and rendering tumor cells resistant to CD8+ T cell-mediated lysis through binding of the Programmed Death-1 (PD-1) receptor. Overexpression of PD-L1 may allow cancer cells to evade the actions of the host immune system. In renal cell carcinoma; upregulation of PD-L1 has been linked to increased tumor aggressiveness and risk of death; and; in ovarian cancer; higher expression of this protein has lead to significantly poorer prognosis. PD-L1 has also been linked to systemic lupus erythematosus and cutaneous melanoma. When considered in adjunct with CD8+ tumor-infiltrating lymphocyte density; expression levels of PD-L1 may be a useful predictor of multiple cancer types; including stage III non-small cell lung cancer; hormone receptor negative breast cancer; and sentinel lymph node melanoma.""
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Recombinant Human PD-L1
- Isotyp:
- Rabbit IgG
- Aufreinigung:
- Protein A/G Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2[o]C - 8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg