Anti-PD-1 Monoclonal Antibody (Clone:IHC001)
Produktgrößen
0.1 ml
£489,00
44-1067-0.1ML
0.5 ml
£634,00
44-1067-0.5ML
Über dieses Produkt
- SKU:
- 44-1067
- Zusätzliche Namen:
- PDCD1||PD1
- translate.label.attr.clone:
- IHC001
- Klonalität:
- Monoclonal
- Weitere Details:
- Programmed Death 1 (PD-1) is a member of the CD28/CTLA-4 family of T-cell regulators; expressed as a co-receptor on the surface of activated T-cells; B-cells; and macrophages. New studies have suggested that the PD-1/PD-L1 signaling pathway may be linked to anti-tumor immunity; as PD-L1 has been shown to induce apoptosis of activated T cells or inhibit activity of cytotoxic T cells. In comparison to CD10 and Bcl-6; PD-1 is expressed by fewer B cells and has therefore been considered a more specific marker for angioimmunoblastic T-cell lymphoma. Therapies targeted toward the PD-1 receptor have shown remarkable clinical responses in patients with various types of cancer; including non€“small-cell lung cancer; melanoma; and renal-cell cancer.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant human His-PD1
- Isotyp:
- Mouse IgG2b
- Aufreinigung:
- Protein A/G Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2[o]C - 8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg