Anti-TIMP2 Polyclonal Antibody
Produktgrößen
100 μg/vial
£785,00
39-2063-100UG
Über dieses Produkt
- SKU:
- 39-2063
- Zusätzliche Namen:
- Metalloproteinase inhibitor 2; CSC-21K; Tissue inhibitor of metalloproteinases 2; TIMP-2; TIMP2
- Klonalität:
- Polyclonal
- Weitere Details:
- TIMP metallopeptidase inhibitor 2; a tissue inhibitor of metalloproteinases; also known as TIMP2; is a human gene; thought to be a metastasis suppressor. This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases; a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases; the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result; the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors; and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
- Format:
- Lyophilized
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide corresponding to a sequence at the C-terminus of human TIMP2(205-220aa RGAAPPKQEFLDIEDP); identical to the related mouse and rat sequences.
- Isotyp:
- Rabbit IgG
- Aufreinigung:
- Immunogen affinity purified.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- At -20[o]C for one year. After reconstitution; at 4[o]C for one month. It can also be aliquotted and stored frozen at -20[o]C for a longer time. Avoid repeated freezing and thawing.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg