Anti-SOCS1 Polyclonal Antibody
Produktgrößen
100 μg/vial
£785,00
39-2061-100UG
Über dieses Produkt
- SKU:
- 39-2061
- Zusätzliche Namen:
- Suppressor of cytokine signaling 1; SOCS-1; JAK-binding protein; JAB; STAT-induced STAT inhibitor 1; SSI-1; Tec-interacting protein 3; TIP-3; SOCS1; SSI1; TIP3
- Klonalität:
- Polyclonal
- Weitere Details:
- Suppressor of cytokine signaling 1(SOCS1); also known as Jak-binding protein(JAB); is a negative regulator to a subset of protein-tyrosine kinases. This 211-amino acid protein has a molecular mass of about 23.5 kD. The TEC-binding region of SOCS1 resides in the N terminus. SOCS1 associates with Tec and suppresses its kinase activity. The SOCS1 gene is intronless and is mapped to on chromosome 16p13.13. SOCS1 regulates the JAK/STAT signal-transduction pathway. Moreover; it contributes to protection against hepatic injury and fibrosis; and may also protect against hepatocarcinogenesis.
- Format:
- Lyophilized
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide corresponding to a sequence at the C-terminus of human SOCS1(197-211aa NPVLRDYLSSFPFQI); identical to the related mouse and rat sequences.
- Isotyp:
- Rabbit IgG
- Aufreinigung:
- Immunogen affinity purified.
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- At -20[o]C for one year. After reconstitution; at 4[o]C for one month. It can also be aliquotted and stored frozen at -20[o]C for a longer time. Avoid repeated freezing and thawing.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:download_pdf.php
