Anti-CCR5 Polyclonal Antibody
Produktgrößen
100 μg/vial
£785,00
39-2032-100UG
Über dieses Produkt
- SKU:
- 39-2032
- Zusätzliche Namen:
- C-C chemokine receptor type 5; C-C CKR-5; CC-CKR-5; CCR-5; MIP-1 alpha receptor; CD195; Ccr5; Cmkbr5
- Klonalität:
- Polyclonal
- Weitere Details:
- Human CC chemokine receptor 5(CCR5); which is 17.5 kb from the CMKBR2 gene; encodes a 352-amino acid protein with a calculated molecular mass of 40;600 Da. It is organized into four exons and two introns. Human CCR5 is a co-receptor for macrophage-tropic strains of human immunodeficiency virus(HIV)-1 and is expressed by bone-marrow-derived cells. CCR5 is expressed on neurons; astrocytes; and microglia in the central nervous system; and on epithelium; endothelium; vascular smooth muscle and fibroblasts in other tissues. Functionally; CCR5 mediates the activation of cells by the chemokines macrophage inflammatory protein-1alpha; macrophage inflammatory protein-1beta; and RANTES; and serves as a fusion cofactor for macrophage-tropic strains of human immunodeficiency virus type 1.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide corresponding to a sequence in the middle region of mouse CCR5(181-199aa SPHFPHTQYHFWKSFQTLK).
- Isotyp:
- Rabbit IgG
- Aufreinigung:
- Immunogen affinity purified.
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- At -20[o]C for one year. After reconstitution; at 4[o]C for one month. It can also be aliquotted and stored frozen at -20[o]C for a longer time. Avoid repeated freezing and thawing.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg