Anti-Bax Polyclonal Antibody
Produktgrößen
100 μg/vial
£785,00
39-2027-100UG
Über dieses Produkt
- SKU:
- 39-2027
- Zusätzliche Namen:
- Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4; BAX; BCL2L4
- Klonalität:
- Polyclonal
- Weitere Details:
- Apoptosis regulator BAX; also known as bcl-2-like protein 4; is a protein that in humans is encoded by the BAX gene. The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as Anti-or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2; and functions as an apoptotic activator. Additionally; this protein is reported to interact with; and increase the opening of; the mitochondrial voltage-dependent anion channel (VDAC); which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants; which encode different isoforms; have been reported for this gene.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide corresponding to a sequence at the N-terminus of human Bax(19-33aa IMKTGALLLQGFIQD); different from the related mouse and rat sequences by one amino acid.
- Isotyp:
- Rabbit IgG
- Aufreinigung:
- Immunogen affinity purified.
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- At -20[o]C for one year. After reconstitution; at 4[o]C for one month. It can also be aliquotted and stored frozen at -20[o]C for a longer time. Avoid repeated freezing and thawing.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg