Anti-Angiopoietin 2 Polyclonal Antibody
Produktgrößen
100 μg/vial
£785,00
39-2016-100UG
Über dieses Produkt
- SKU:
- 39-2016
- Zusätzliche Namen:
- Angiopoietin-2; ANG-2; ANGPT2
- Klonalität:
- Polyclonal
- Weitere Details:
- Angiopoietin 1 and Angiopoietin 2 are important for development of the endothelium; by regulating tyrosine phosphorylation of the membrane receptor Tie 2. Angiopoietin 2 is only 60% homologous with Angiopoietin 1. Angiopoietin-2 is a naturally occurring antagonist of angiopoietin-1 that competes for binding to the TIE2 receptor and blocks ANGPT1-induced TIE2 autophosphorylation. Angiopoietin 1 binding to Tie 2 causes phosphorylation of the receptor. Angiopoietin 2 competes for this binding; and thus blocks receptor phosphorylation. Angiopoietin 2 expression occurs at sites of vascular remodelling: dorsal aorta and major aortic branches; ovary; placenta and uterus.
- Format:
- Lyophilized
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide corresponding to a sequence at the C-terminus of human Angiopoietin 2(454-468aa NLNGMYYPQRQNTNK).
- Isotyp:
- Rabbit IgG
- Aufreinigung:
- Immunogen affinity purified.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- At -20[o]C for one year. After reconstitution; at 4[o]C for one month. It can also be aliquotted and stored frozen at -20[o]C for a longer time. Avoid repeated freezing and thawing.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg