Anti-p53 Monoclonal Antibody (Clone: BP53-12)
Produktgrößen
100 μg/vial
£785,00
39-1049-100UG
Über dieses Produkt
- SKU:
- 39-1049
- Zusätzliche Namen:
- Cellular tumor antigen p53; Tumor suppressor p53; Tp53; P53
- translate.label.attr.clone:
- BP53-12
- Klonalität:
- Monoclonal
- Weitere Details:
- The p53 tumor antigen is found in increased amounts in a wide variety of transformed cells. The protein is also detectable in many actively proliferating; nontransformed cells; but it is undetectable or present at low levels in resting cells. This protein induces cell cycle arrest or apoptosis in response to sublethal or severe DNA damage; respectively; by differential transcription of target genes and through transcription-independent apoptotic functions. The p53 protein contains 393 amino acids. Human p53 tumour antigen is Locatedto band 17p13. p53 mutations are common in pancreatic cancer and are absent in chronic pancreatitis.
- Host:
- Mouse
- Immunogen:
- Recombinant human wild-type p53 protein.
- Isotyp:
- Mouse IgG2a
- Aufreinigung:
- Ascites
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- At -20[o]C for one year. After reconstitution; at 4[o]C for one month. It can also be aliquotted and stored frozen at -20[o]C for a longer time. Avoid repeated freezing and thawing.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
