Anti-c-Myc Monoclonal Antibody (Clone: 9E10)
Produktgrößen
100 μg/vial
£785,00
39-1025-100UG
Über dieses Produkt
- SKU:
- 39-1025
- Zusätzliche Namen:
- Myc proto-oncogene protein; Proto-oncogene c-Myc; Transcription factor p64; Myc
- translate.label.attr.clone:
- 9E10
- Klonalität:
- Monoclonal
- Weitere Details:
- C-Myc is an oncogene that functions both in the stimulation of cell proliferation and in apoptosis. c-Myc elicits its oncogenic activity by causing immortalization; and to a lesser extent the transformation of cells; in addition to several other mechanisms. The c-MYC proto-oncogene encodes a transcription factor that is critical for cell growth and proliferation. It is one of the genes frequently altered in cancer cells in which it exhibits constitutive activity. Downregulation of c-Myc is critical for 2-Methoxyestradiol(2ME2)-induced oxidative stress and apoptosis in AML cells. And its up-regulation is important for promoting lymphocyte cell division; and demonstrating that GFP-c-Myc expression is a marker of proliferating lymphocytes in vivo.
- Host:
- Mouse
- Immunogen:
- Synthetic peptide corresponding to residues 408-439 of the human p62c-Myc protein.
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- Ascites
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- At -20[o]C for one year. After reconstitution; at 4[o]C for one month. It can also be aliquotted and stored frozen at -20[o]C for a longer time. Avoid repeated freezing and thawing.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg