Recombinant Monoclonal Antibody to TRIM29 (Lung Squamous Cell Carcinoma Marker)(Clone : TRIM29/9257R)
Produktgrößen
100ug
£716,00
36-3828-100UG
Über dieses Produkt
- SKU:
- 36-3828
- Anwendung:
- IHC-Frozen
- translate.label.attr.clone:
- TRIM29/9257R
- Klonalität:
- Monoclonal
- Weitere Details:
- It recognizes a 66kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90% positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.
- Gendetails:
- TRIM29
- Host:
- Rabbit
- Isotyp:
- IgG / Kappa
- Aufreinigung:
- Prepared in 1mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
