Anti-CD40; Mouse Monoclonal Antibody(Clone: FGK45.5)
Produktgrößen
20 µg
£397,00
36-3821-20UG
100 µg
£716,00
36-3821-100UG
Über dieses Produkt
- SKU:
- 36-3821
- Zusätzliche Namen:
- B cell surface antigen CD40; CD40 type II isoform; p50; Bp50; CD40L receptor; CDW40; TRAP; IMD3; IGM; Tnfrsf5; HIGM1; GP39; T-BAM
- translate.label.attr.clone:
- FGK45.5
- Klonalität:
- Monoclonal
- Weitere Details:
- Upon binding to its ligand CD154; CD40 acts as a costimulatory molecule for the activation of B cells; dendritic cells; monocytes; and other APCs. CD40 plays roles in B cell activation; differentiation; proliferation and Ig isotype switching as well as dendritic cell maturation. FGK4.5 can be used for blocking of CD40/CD154 interaction and forin vitroandin vivoactivation of CD40 expressing APCs. This MAb is shown to indirectly activate natural killer (NK) cells; producing significant antitumor and anti-metastatic effects. Effective in boosting immune responses against infectious agents and can potentially be used to treat chronic autoimmune inflammatory processes.
- Host:
- Rat
- Immunogen:
- Purified recombinant Mouse CD40 fusion protein
- Isotyp:
- Rat IgG2a; kappa
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php