Anti-PD1; Mouse Monoclonal Antibody(Clone: RMP1-14)
Produktgrößen
20 µg
£397,00
36-3818-20UG
100 µg
£716,00
36-3818-100UG
Über dieses Produkt
- SKU:
- 36-3818
- Zusätzliche Namen:
- CD279; CD279 antigen; PD1; PDCD1; Programmed cell death 1; Programmed cell death protein 1; Systemic lupus erythematosus susceptibility 2 (SLEB2)
- translate.label.attr.clone:
- RMP1-14
- Klonalität:
- Monoclonal
- Weitere Details:
- PD-1 is expressed on a subset of CD4-CD8-thymocytes; and on activated T and B cells. PD-1 is thoµght to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands; PD-L1 (also known as B7-H1) and PD-L2 (B7-DC); are members of the B7 immunoglobulin superfamily. PD-1 is transiently expressed on CD4 and CD8 thymocytes as well as activated T and B-lymphocytes and myeloid cells. Additionally;Pdcd1mRNA is expressed in developing B-lymphocytes during the pro-B-cell stage. The RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production co-stimulated by macrophages (but not by dendritic cells and B cells).
- Host:
- Rat
- Immunogen:
- PDCD1 transfected BHK cells
- Isotyp:
- Rat IgG2a; kappa
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg