Anti-HLA-Pan (MHC II) Monoclonal Antibody(Clone: HLA-Pan/2967R)
Produktgrößen
20 µg
£397,00
36-3798-20UG
100 µg
£716,00
36-3798-100UG
Über dieses Produkt
- SKU:
- 36-3798
- Zusätzliche Namen:
- HLA-DPB1; HLA-DQA1; HLA-DQB1; HLA-DRA; HLA-DRB1; HLA-DRB3; HLA-DRB4; HLA-DRB5
- translate.label.attr.clone:
- HLA-Pan/2967R
- Klonalität:
- Monoclonal
- Weitere Details:
- Reacts with a common epitope of human major histocompatibility (MHC) class II antigens; HLA-DP; -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36kDa) and a chain (27kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes; monocytes; macrophages; and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci; DR; DQ and DP; encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They; therefore; have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
- Host:
- Rabbit
- Immunogen:
- Non-T; non-B human acute lymphoblastic leukemia REH6 cell line
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
