Anti-HPV16 E1/E4 (Human Papilloma Virus 16) Monoclonal Antibody(Clone: HPV16 E1/E4)
Produktgrößen
20 µg
£397,00
36-3796-20UG
100 µg
£716,00
36-3796-100UG
Über dieses Produkt
- SKU:
- 36-3796
- Zusätzliche Namen:
- HPV-16; HPV-16 capsid; HPV16 L1; HPV16 major capsid protein L1; Human papillomavirus type 16 L1; Human papillomavirus type 16 major capsid protein L1
- translate.label.attr.clone:
- HPV16 E1/E4
- Klonalität:
- Monoclonal
- Weitere Details:
- The human papilloma virus (HPV) family of DNA tumor viruses includes HPV16; a 'high-risk' sexually-transmitted HPV that can lead to cervical; anal; vulvar; head; neck; and penile cancer. The HPV16E1/E4 protein is expressed abundantly in cells supporting viral DNA amplification; but is lost during malignant progression. HPV16E1/E4 causes G2 cell cycle arrest by associating with and preventing the nuclear entry of Cdk1/cyclin B1 complexes. HPV16E1/E4 also interacts with cyclin A and Cdk2 during the G2 phase of the cell cycle; and this association may increase the efficiency with which HPV16E1/E4 is able to prevent mitotic entry. HPV16E1/E4 also associates with keratin intermediate filaments and causes the network to collapse.
- Host:
- Mouse
- Immunogen:
- Recombinant human HPV16 E1/E4 fragment (aa 36-41).
- Isotyp:
- Mouse IgG1; kappa
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
