Anti-Vitronectin Receptor / CD51 / CD61 Monoclonal Antibody(Clone: 23C6)
Produktgrößen
20 µg
£397,00
36-3701-20UG
100 µg
£716,00
36-3701-100UG
Über dieses Produkt
- SKU:
- 36-3701
- Zusätzliche Namen:
- CD51; DKFZp686A08142; integrin alpha V beta 3; Integrin alpha-5 Integrin alpha-V light chain; integrin alphaVbeta3; integrin; alpha V (vitronectin receptor; alpha polypeptide; antigen CD51); ITGAV; Msk8; VNRA; VTNR
- translate.label.attr.clone:
- 23C6
- Klonalität:
- Monoclonal
- Weitere Details:
- ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains; that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1;3;5;6; and 8; 'ITGB1'; 'ITGB3'; 'ITGB5'; 'ITGB6'; and 'ITGB8'); each can interact with extracellular matrix ligands; the alpha V beta 3 integrin; perhaps the most studied of these; is referred to as the Vitronectin Receptor (VNR). In addition to adhesion; many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants. Reacts with Integrin Alpha V Beta 3. 23C6 may be useful for bone resorption modulation; osteoclast identification; receptor purification; malignant melanoma identification and treatment.
- Host:
- Mouse
- Immunogen:
- Osteoclasts from osteoclastomas
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg