Anti-HPV-18 (Human Papilloma Virus 18) Monoclonal Antibody(Clone: HPV18/1297)
Produktgrößen
20 µg
£397,00
36-3698-20UG
100 µg
£716,00
36-3698-100UG
Über dieses Produkt
- SKU:
- 36-3698
- Zusätzliche Namen:
- E6; Human Papilloma Virus; HPV type 18 E6; Protein E6
- translate.label.attr.clone:
- HPV18/1297
- Klonalität:
- Monoclonal
- Weitere Details:
- Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximately 90% of cervical cancers contain HPV DNA of the high risk types. Mutational analysis has shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB; respectively; correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins; and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro.
- Host:
- Mouse
- Immunogen:
- HPV18 E6-β-galactosidase fusion protein
- Isotyp:
- Mouse IgG1; kappa
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
