Anti-Major Vault Protein (MVP) Monoclonal Antibody(Clone: VP2897R)
Produktgrößen
20 µg
£397,00
36-3671-20UG
100 µg
£716,00
36-3671-100UG
Über dieses Produkt
- SKU:
- 36-3671
- Zusätzliche Namen:
- Lung resistance-related protein (LRP); Major Vault Protein; MVP; VAULT1
- translate.label.attr.clone:
- VP2897R
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a protein of 104kDa-110kDa; characterized as major vault protein (MVP). Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology; including several small molecules of RNA; but a single protein species. The MVP accounts for 70% of their mass. Their shape is reminiscent of the nucleopore central plµg. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to estrogen; progesterone and glucocorticoid receptors are able to co-immunoprecipitate the MVP. MVP is overexpressed in many neoplastic tissues and cell lines. Expression of MVP predicts a poor response to chemotherapy.
- Host:
- Rabbit
- Immunogen:
- Recombinant full-length human MVP protein
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
