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Antikörper

Anti-CD79a (B-Cell Marker) Monoclonal Antibody(Clone: IGA/1688R)

Produktgrößen
20 µg
£397,00
36-3657-20UG
100 µg
£716,00
36-3657-100UG
Über dieses Produkt
SKU:
36-3657
Zusätzliche Namen:
B lymphocyte-specific MB1 protein; B-cell antigen receptor complex-associated protein alpha chain; CD79a molecule immunoglobulin associated alpha; Ig-alpha; IGA; IgM-alpha; Immunoglobulin-associated alpha; Ly54; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; Surface Ig
translate.label.attr.clone:
IGA/1688R
Klonalität:
Monoclonal
Weitere Details:
A disulphide-linked heterodimer; consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides; is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B cell Ag receptor. CD79a first appears at pre B cell stage; early in maturation; and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type; in B cell lines; B cell lymphomas; and in some myelomas. It is not present in myeloid or T cell lines. Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20; but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well.
Host:
Rabbit
Immunogen:
A synthetic peptide corresponding to aa 202-216 (GTYQDVGSLNIADVQ) of human CD79a protein
Isotyp:
Rabbit IgG
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody
  • Datenblatt des Herstellers:1.jpg
Fig. 2: SDS-PAGE Analysis of Purified CD79a Rabbit Recombinant Monoclonal Antibody (IGA/1688R).
Fig. 3: Western Blot Analysis of human Raji cell lysate using CD79a Rabbit Recombinant Monoclonal Antibody (IGA/1688R).
Fig. 4: Flow Cytometric Analysis of Raji cells using CD79a Rabbit Recombinant Monoclonal Antibody (IGA/1688R) followed by Goat anti-rabbit IgG-CF488 (Blue); Isotype Control (Red).
Fig. 4: Flow Cytometric Analysis of Raji cells using CD79a Rabbit Recombinant Monoclonal Antibody (IGA/1688R) followed by Goat anti-rabbit IgG-CF488 (Blue); Isotype Control (Red).
Fig. 5: Immunofluorescence Analysis of PFA-fixed Raji cells labeling CD79a with CD79a Rabbit Recombinant Monoclonal Antibody (IGA/1688R) followed by Goat anti-rabbit IgG-CF488 (Green). The nuclear counterstain is Reddot (Red)