Anti-CD63 (Late Endosomes Marker) Monoclonal Antibody(Clone: NKI/C3)-CF488
Produktgrößen
0.5 at 100 ml at µg/ml
£716,00
36-3633-0.5AT100MLATUG
Über dieses Produkt
- SKU:
- 36-3633
- Zusätzliche Namen:
- gp55; granulophysin; Lysosomal-associated membrane protein 3 (LAMP-3); Mast cell antigen AD1; melanoma 1 antigen; Melanoma-associated antigen MLA1; Melanoma-associated antigen ME491; MLA1; NGA; Ocular melanoma-associated antigen; OMA81H; PTLGP40; Tetraspanin-30; TSPAN30
- translate.label.attr.clone:
- NKI/C3
- Klonalität:
- Monoclonal
- Konjugat:
- CF488
- Weitere Details:
- This MAb recognizes protein of 26kDa-60kDa; which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets; monocytes and macrophages; and is weakly expressed on granulocytes; T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9; CD37 and CD53; which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.
- Host:
- Mouse
- Immunogen:
- Smooth plasma membrane fraction of MeWo cells
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 4 to 8[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
