Anti-CD34 (Hematopoietic Stem Cell & Endothelial Marker) Monoclonal Antibody(Clone: ICO-115)-CF488
Produktgrößen
0.5 at 100 ml at µg/ml
£716,00
36-3587-0.5AT100MLATUG
Über dieses Produkt
- SKU:
- 36-3587
- Zusätzliche Namen:
- Hematopoietic Progenitor Cell Antigen; HPCA1; Mucosialin
- translate.label.attr.clone:
- ICO-115
- Klonalität:
- Monoclonal
- Konjugat:
- CF488
- Weitere Details:
- This antibody recognizes a carbohydrate epitope on a single chain; transmembrane; heavily glycosylated protein of 90-120kDa; which is identified as CD34 (VI international workshop on human differentiation antigens). Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition; it is expressed by soft tissue tumors; such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally; it appears that proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposi's sarcoma; but shows low specificity.
- Host:
- Mouse
- Immunogen:
- Blast cells of a chronic myeloid leukemia patient
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 4 to 8[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg