Anti-CD80 (B7-1) Monoclonal Antibody(Clone: C80/1608)
Produktgrößen
20 µg
£397,00
36-3570-20UG
100 µg
£716,00
36-3570-100UG
Über dieses Produkt
- SKU:
- 36-3570
- Zusätzliche Namen:
- Activation B7-1 antigen; B lymphocyte activation antigen B7; B7; B7-1; BB1; CD28 antigen ligand 1; CD28LG; CD28LG1; CD80; Costimulatory factor CD80; CTLA-4 counter-receptor B7.1; LAB7; T-lymphocyte activation antigen CD80
- translate.label.attr.clone:
- C80/1608
- Klonalität:
- Monoclonal
- Weitere Details:
- T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen; followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that; when engaged; potentiates T cell expansion in a CD28-independent manner. B7; also designated BB1; is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human CD80 protein
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg