Anti-MUC16 / CA125 (Ovarian Carcinoma Marker) Monoclonal Antibody(Clone: MUC16/1860)
Produktgrößen
20 µg
£397,00
36-3567-20UG
100 µg
£716,00
36-3567-100UG
Über dieses Produkt
- SKU:
- 36-3567
- Zusätzliche Namen:
- CA125; Cancer antigen 125; MUC16; Mucin16; Ovarian cancer-related tumor marker CA125; Ovarian carcinoma antigen CA125
- translate.label.attr.clone:
- MUC16/1860
- Klonalität:
- Monoclonal
- Weitere Details:
- The mucins are a family of highly glycosylated; secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial Mucins are large; secreted and cell surface glycoproteins crucial for adhesion modulation; signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4; Mucin 5 (AC and B); Mucins 6-8; Mucins 11-13 and Mucins 15-17. The Mucin 16 protein (also commonly referred to as CA125); encoded for by the gene MUC16; is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain; an extracellular domain and an amino terminal domain. Mucin 16; an ovarian cancer-associated antigen; is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.
- Host:
- Mouse
- Immunogen:
- Full length native MUC16 protein Purified from human ovarian carcinoma
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
