Anti-CD7 (T-Cell Leukemia Marker) Monoclonal Antibody(Clone: B-F12)
Produktgrößen
20 µg
£397,00
36-3505-20UG
100 µg
£716,00
36-3505-100UG
Über dieses Produkt
- SKU:
- 36-3505
- Zusätzliche Namen:
- GP40; Leu9; p41; T-cell leukemia antigen; T-cell surface antigen Leu-9; Tp40; TP41
- translate.label.attr.clone:
- B-F12
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a protein of 40kDa; identified as CD7 (also known as gp40; Leu9). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes; and T cell leukemia. It is also found on natural killer cells; a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes; expression of adhesion molecules; cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
- Host:
- Mouse
- Immunogen:
- Chronic Lymphoid Leukemia cells (CLL)
- Isotyp:
- Mouse IgG2a; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg