Anti-CD4 (T-Helper/Inducer Cell Marker) Monoclonal Antibody(Clone: CD4/1604)
Produktgrößen
20 µg
£397,00
36-3489-20UG
100 µg
£716,00
36-3489-100UG
Über dieses Produkt
- SKU:
- 36-3489
- Zusätzliche Namen:
- L3T4; Leu3; Ly-4; Lymphocyte antigen CD4; p55; T cell antigen T4/LEU3; T cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4
- translate.label.attr.clone:
- CD4/1604
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a protein of 55kDa; identified as CD4. It is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes; but also in B cells; macrophages; and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or aµgment the early phase of T-cell activation; and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. The majority of peripheral T-cell lymphomas are derived from the T-helper/regulatory cell subset so that most mature T-cell neoplasms are CD4+/CD8-. Anti-CD4 is used in the immunohistochemical staining of lymphoproliferative disorders to evaluate tumors with CD4 aberrant expression.
- Host:
- Mouse
- Immunogen:
- Recombinant human CD4 protein fragment (around aa 245-392) (exact sequence is proprietary)
- Isotyp:
- Mouse IgG2b; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg