Anti-CD137L / 4-1BBL / TNFSF9 Monoclonal Antibody(Clone: CD137L/1547)
Produktgrößen
20 µg
£397,00
36-3431-20UG
100 µg
£716,00
36-3431-100UG
Über dieses Produkt
- SKU:
- 36-3431
- Zusätzliche Namen:
- 4-1BB ligand; 4-1BBL; CD137L; ILA ligand (TNF related); Ly63l; Tumor necrosis factor ligand 5A (TNLG5A); Tumor necrosis factor ligand superfamily member 9 (TNFSF9)
- translate.label.attr.clone:
- CD137L/1547
- Klonalität:
- Monoclonal
- Weitere Details:
- TNFSF9 / 4-1BBL is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9 / 4-1BB; which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9 / 4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. It has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine is required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines; and is thoµght to be involved in T cell-tumor cell interaction.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human CD137L protein
- Isotyp:
- Mouse IgG2a; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
