Anti-p63 (Squamous; Basal & Myoepithelial Cell Marker) Monoclonal Antibody(Clone: TP63/1786)
Produktgrößen
20 µg
£397,00
36-3424-20UG
100 µg
£716,00
36-3424-100UG
Über dieses Produkt
- SKU:
- 36-3424
- Zusätzliche Namen:
- Amplified in squamous cell carcinoma (AIS); Chronic ulcerative stomatitis protein (CUSP); EEC3; Keratinocyte transcription factor KET; LMS; NBP; p40; P51/P63; p53 like transcription factor; p53-related protein p63; RHS; SHFM4; TAp63alpha; TP53CP; TP53L; TP63; TP73; TP73L; Transformation-related prot
- translate.label.attr.clone:
- TP63/1786
- Klonalität:
- Monoclonal
- Weitere Details:
- p63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues; including epidermis; cervix; urothelium; breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands; however; it was not expressed in malignant tumors of the prostate. As a result; p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate; particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC); with a sensitivity of ~90%. Specificity for lung SqCC; vs. lung adenocarcinoma (LADC); is approximately 80%. In breast tissue; p63 has been identified in myoepithelial cells of normal ducts.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 3-106) of human p63 protein (exact sequence is proprietary)
- Isotyp:
- Mouse IgG2b; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
