Anti-BAP1 (BRCA1 Associated Protein 1) Monoclonal Antibody(Clone: BAP1/2431)
Produktgrößen
20 µg
£397,00
36-3417-20UG
100 µg
£716,00
36-3417-100UG
Über dieses Produkt
- SKU:
- 36-3417
- Zusätzliche Namen:
- BAP1; BRCA1 associated protein 1; Cerebral protein 13; Cerebral protein 6; HUCEP 13; Hucep 6; HUCEP13; Hucep6; TPDS; Ubiquitin carboxy terminal hydrolase; Ubiquitin carboxyl terminal hydrolase BAP1; UCHL2
- translate.label.attr.clone:
- BAP1/2431
- Klonalität:
- Monoclonal
- Weitere Details:
- The BAP1 gene belongs to the ubiquitin C-terminal hydrolase subfamily of de-ubiquitination enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition; the enzyme may be involved in regulation of transcription; regulation of cell cycle and growth; response to DNA damage and chromatin dynamics. Germ line mutations in this gene may be associated with tumor predisposition syndrome (TPDS); which involves increased risk of cancers including malignant mesothelioma; Uveal melanoma and cutaneous melanoma.
- Host:
- Mouse
- Immunogen:
- Recombinant human BAP1 protein fragment (around aa 191-326) (exact sequence is proprietary)
- Isotyp:
- Mouse IgG2c; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
